Prof. Dr. Jutta Eichler

Professur für Pharmazeutische Chemie

The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity (2022) Schweininger J, Kriegel M, Häge S, Conrad M, Alkhashrom S, Lösing J, Weiler S, et al. Journal article A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro (2022) Aillaud I, Kaniyappan S, Chandupatla RR, Ramirez LM, Alkhashrom S, Eichler J, Horn A, et al. Journal article A PROSS-designed extensively mutated estrogen receptor α variant displays enhanced thermal stability while retaining native allosteric regulation and structure (2021) Kriegel M, Wiederanders HJ, Alkhashrom S, Eichler J, Muller Y Journal article A pair of non‐competing neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model (2021) Peter AS, Roth E, Schulz S, Fraedrich K, Steinmetz T, Damm D, Hauke M, et al. Journal article, Original article Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors (2021) Alkhashrom S, Kicuntod J, Häge S, Schweininger J, Muller Y, Lischka P, Marschall M, Eichler J Journal article Properties of Oligomeric Interaction of the Cytomegalovirus Core Nuclear Egress Complex (NEC) and Its Sensitivity to an NEC Inhibitory Small Molecule (2021) Kicuntod J, Alkhashrom S, Häge S, Diewald B, Müller R, Hahn F, Lischka P, et al. Journal article Exploring Viral Interference Using Peptides: Molecular Determinants of HIV-1 Inhibition by a Peptide Derived from Human Pegivirus-1 Envelope Protein E2 (2021) Hoffmann R, Ruegamer T, Schaubaecher J, Rohrhofer A, Kirmeß P, Fiebig K, Schmidt B, Eichler J Journal article Systematic Evaluation of Fluorination as Modification for Peptide-Based Fusion Inhibitors against HIV-1 Infection (2021) Huhmann S, Nyakatura EK, Rohrhofer A, Moschner J, Schmidt B, Eichler J, Roth C, Koksch B Journal article Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects (2020) Tomasovic A, Brand T, Schanbacher C, Kramer S, Hümmert MW, Godoy P, Schmidt-Heck W, et al. Journal article Nuclear Egress Complexes of HCMV and Other Herpesviruses: Solving the Puzzle of Sequence Coevolution, Conserved Structures and Subfamily-Spanning Binding Properties (2020) Marschall M, Häge S, Conrad M, Alkhashrom S, Kicuntod J, Schweininger J, Kriegel M, et al. Journal article, Review article